Technological advances such as global positioning, telematics, RFID, wireless communication, etc. enable companies to achieve near real-time visibility over assets in transit. Despite such technological advances, it appears that many global supply chains still suffer from the lack of visibility. While determining the costs for deploying systems to provide visibility is relatively easy, there is little basis for determining the business value that can be generated with near real-time information on assets in transit. Obviously, the availability of data is not a value by itself; realtime data on assets in transit must be converted into useful information that enables actions which generate business value. The focus of this joint research is to develop a framework approach and analytical tool to assess the value that can be generated with In-Transit Visibility. Based on interviews with DHL experts and survey results, we propose a variety of in-transit actions with the associated value potential and position them within a framework of various supply chain strategies, product characteristics, and operating environments. Some context-specific case studies illustrate the value assessment approach. Additionally, we developed a simulation model to calculate the value of deploying different levels of visibility. This analytical tool is flexible enough to be applied to a variety of supply chain configurations.